Permission Denied: Creating Lock File Hitching Post [DirectAdmin]

This can happen if the file permissions on the spool files for the emails are incorrect. Run the following to reset them:

chmod 1777 /var/spool/mail
chown mail:mail /var/spool/mail
chmod 1777 /var/spool/virtual
chown mail:mail /var/spool/virtual

and for each domain you have, (eg domain.com for user username)

chmod 770 /var/spool/virtual/domain.com
chown username:mail /var/spool/virtual/domain.com